GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9902453 | 1 | rs4074170 | chr17:28381141 | EFCAB5 | chr17:28256874-28435469:+ | -0.22 | -3.84 | 0.000147 | Coffee consumption (cups per day) |
| BLCA | cis | rs9894429 | 1 | rs4074915 | chr17:79579230 | TSPAN10 | chr17:79609349-79615778:+ | -0.49 | -8.84 | 3.52E-17 | Eye color traits |
| BLCA | cis | rs9894429 | 1 | rs4074916 | chr17:79579248 | TSPAN10 | chr17:79609349-79615778:+ | -0.49 | -8.84 | 3.52E-17 | Eye color traits |
| BLCA | cis | rs9457247 | 1 | rs407515 | chr6:167407544 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.05 | 7.0E-7 | Crohn's disease |
| BLCA | cis | rs4075511 | 1 | rs4075511 | chr2:18243534 | KCNS3 | chr2:18059114-18114224:+ | 0.24 | 3.92 | 0.000106 | Temperament (bipolar disorder) |
| BLCA | cis | rs9902453 | 1 | rs4075623 | chr17:28386526 | EFCAB5 | chr17:28256874-28435469:+ | -0.23 | -4 | 7.57E-5 | Coffee consumption (cups per day) |
| BLCA | cis | rs2275426 | 1 | rs4076006 | chr1:46438076 | CCDC163P | chr1:45960581-45965646:- | -0.34 | -6.43 | 3.87E-10 | Body mass index |
| BLCA | cis | rs9457247 | 1 | rs408040 | chr6:167398903 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.1 | 5.43E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs408080 | chr6:167392522 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -4.96 | 1.04E-6 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs408087 | chr6:167398952 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.06 | 6.52E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs408918 | chr6:167399282 | RNASET2 | chr6:167343008-167412795:- | -0.22 | -4.62 | 5.33E-6 | Crohn's disease |
| BLCA | cis | rs454422 | 1 | rs409035 | chr20:5943649 | MCM8 | chr20:5931298-5975829:+ | -0.21 | -4.39 | 1.45E-5 | HIV-1 viral setpoint |
| BLCA | cis | rs9457247 | 1 | rs409356 | chr6:167405226 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.15 | 4.08E-7 | Crohn's disease |
| BLCA | cis | rs2243480 | 1 | rs410128 | chr7:65603173 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.13 | 4.46E-5 | Diabetic kidney disease |
| BLCA | cis | rs11723261 | 1 | rs4129956 | chr4:302008 | ZNF718 | chr4:53272-156488:+ | 0.35 | 4.61 | 5.42E-6 | Immune response to smallpox vaccine (IL-6) |